Looking for genes associated with idiopathic generalised epilepsy
Dr Andrew Makoff and his team at the Institute of Psychiatry in London will carry out a study on 469 DNA samples from patients with idiopathic generalised epilepsy (IGE) and their parents and some cont [...]
Storage capacity for an Epilepsy DNA Biobank
£9,600 (equipment grant) Professor Mark Rees, School of Medicine, University of Wales Swansea [...]
Excessive neurotransmitter release during seizures – how and why?
Dr Michael Cousin of the University of Edinburgh will be looking at neurotransmitters, this time at the cellular processes that govern their release. Neurotransmitters are essential to normal brain act [...]
Electrical activity in the brain just before a seizure starts
The area of the brain in which seizures start is called the seizure focus. In this area, the normal electrical signalling of the brain is not always totally controlled. If the excitability gets out of [...]
The role of Ih in the entorhinal cortex during the latent period
£60,000 over 12 months (project grant) Dr Mala Shah, Department of Pharmacology, University College London; Dr Matthew Walker, Department of Clinical and Experimental Epilepsy, Institute of Neurology, [...]
Long-term neuropsychological follow-up of children who had neurosurgical treatment for the relief of temporal lobe epilepsy
£64,828 over 18 months (project grant) Dr Torsten Baldeweg, Department of Developmental Cognitive Neuroscience, Institute of Child Health, University College London; Dr J Helen Cross, Neurosciences Uni [...]
Neurotransmitter receptor distribution in patients with TLE due to hippocampal sclerosis
Hippocampal sclerosis is a thickening and hardening of the brain tissue in the hippocampus. It is a very common feature of TLE. This sort of epilepsy is frequently not treatable with AEDs, but responds [...]
Evaluation of anti-epileptic drug action using in vivo micro-SPECT imaging
£59,382 over 12 months (project grant) Dr Graeme Sills, Division of Cardiovascular and Medical Sciences, University of Glasgow; Dr Deborah Dewar, Division of Clinical Neuroscience, University of Glasgo [...]
The types of epilepsy seen in very young children
Most children with epilepsy develop the condition in their first year of life. However, a wide variety of seizure types and syndromes are seen, and their later development differs. Some children develo [...]
Neuronal aggregate formation in epileptic foci: a combined clinical and experimental study
£65,202 over 24 months (project grant) Professor John Jefferys, and Dr John Fox, Division of Neuroscience (Neurophysiology), Medical School, University of Birmingham [...]
The role of plasma membrane Ca2+ ATPases in the regulation of neuronal [Ca2+]i in an in vitro model of epilepsy
£23,000 over 24 months (fellowship grant) Mr Thomas Jensen and Dr Ruth Empson, School of Biological Sciences, Royal Holloway University of London [...]
Tonic GABAA receptor signalling in epilepsy
£49,023 over 12 months (project grant) Dr Matthew Walker, Dr Dimitri Kullmann and Dr Alexey Semyanov, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London [...]
