‘Mossy cells’ are located in the hippocampus, deep within the brain. Their role in epilepsy has been the subject of discussion for many years. New research conducted by Ivan Soltesz, Professor of neurosurgery and neurosciences at Stanford University suggests that they play a vital role in seizures and memory. In this study the research team were able to turn mossy cells on or off to see whether they had any effect on epileptic seizures. By turning on the cells, they were able to prevent focal seizures from turning into convulsive ones. However, when the mossy cells were turned off, convulsive seizures were more likely to occur. Further, preventing the loss of mossy cells or activating them may prove a useful avenue for the development of new therapies for epilepsy. To read more about this research, click here: